Study of the Comparative Microbiome Profile from Different Fecal Preservation Methods
A preview of this application note (paraphrased from the introduction):
The role of the gut microbiome in human health and disease has become a significant research focus in recent years, with researchers moving to explore the relationship between the human microbiome and diseases such as diabetes and cancer. Fecal sampling provides a powerful and non-invasive tool for in-depth analysis of host-microbiome interactions. Since fecal microbiota sequencing profiles have been shown to change significantly during ambient temperature storage, inappropriate sample handling or storage can critically impact microbiome profiling results. Through a comparative microbiome profile, this study assesses the quality of the standard -80°C preservation protocol against two popular commercial preservation options, including Norgen Biotek’s Stool Nucleic Acid Collection and Preservation Tubes.