Introducing Micronic TPE Lyophilization Caps

Optimizing lyophilization workflows with Micronic TPE Lyophilization Caps

Lyophilization, also known as freeze-drying, is widely used to preserve biological and pharmaceutical samples for long-term storage. While the process effectively removes moisture to improve sample stability, it also requires a sealing solution that allows vapor release without compromising sample protection.

To meet this need, Micronic has expanded its sample storage portfolio with the Micronic TPE Lyophilization Caps. Developed specifically for 96-well sample storage tubes, these caps combine a vented design with efficient rack-based capping, helping laboratories streamline freeze-drying workflows while maintaining confidence in sample handling.

Discover the complete lyophilization solution

 
 

Why choose Micronic TPE Lyophilization Caps?

Designed specifically for freeze-drying applications, the Micronic TPE Lyophilization Caps provide a reliable solution for laboratories working with sensitive samples.

The key benefits include:

  • Controlled moisture vapor release during lyophilization
  • Secure sealing throughout the freeze-drying process
  • Faster capping with the Capcluster-96 format
  • Compatibility with multiple Micronic tube formats
  • High-quality cleanroom manufacturing

Together, these features support efficient sample processing while helping maintain sample integrity throughout the lyophilization workflow.

Engineered for efficient freeze-drying

The defining feature of the Micronic TPE Lyophilization Caps is their vented design. During the freeze-drying process, moisture vapor can escape through the cap, allowing drying to proceed efficiently while the tube remains securely sealed. This provides a controlled approach to lyophilization without requiring temporary sealing solutions.

Manufactured from Thermoplastic Elastomer (TPE), the caps offer excellent chemical resistance and are suitable for temperatures ranging from -80°C to +100°C (without retaining foil). This makes them suitable for demanding laboratory environments where reliable sample protection is essential.

 

Improve laboratory efficiency

Processing large numbers of samples can be time-consuming when tubes need to be capped individually. The Micronic TPE Lyophilization Caps are supplied in the Capcluster-96 format, enabling an entire 96-well rack to be sealed in a single action.

This rack-based approach helps laboratories:

  • Reduce repetitive manual handling
  • Improve consistency across sample racks
  • Save valuable processing time
  • Support standardized and automated workflows

After application, the retaining foil can be removed so that each tube remains individually sealed. This provides flexibility for downstream applications, allowing samples to be stored, transported, or processed individually without disturbing neighboring tubes.

 

Broad compatibility for everyday use

The Micronic TPE Lyophilization Caps are compatible with Micronic screw cap tubes and push cap tubes with internal thread in the following formats:

  • 0.50 mL
  • 0.75 mL
  • 1.10 mL
  • 1.40 mL
  • 2.00 mL

This broad compatibility allows laboratories to apply a consistent lyophilization sealing solution across multiple sample volumes while simplifying inventory management and workflow standardization.

 

Manufactured to high quality standards

Quality and consistency are essential when working with valuable biological samples. The Micronic TPE Lyophilization Caps are manufactured in an ISO Class 7 cleanroom environment to help minimize contamination risks during production.

Additional product characteristics include:

  • Made from high-quality Thermoplastic Elastomer (TPE)
  • High chemical resistance
  • Available in Natural and EFC Blue-Green
  • Designed for use with Micronic 96-well sample storage systems

 

Supporting reliable sample preservation

Successful lyophilization depends on more than the freeze-drying process itself. Selecting the right sealing solution can improve workflow efficiency, simplify sample handling, and support consistent preservation practices from preparation through long-term storage.

With the introduction of the Micronic TPE Lyophilization Caps, laboratories gain a purpose-built solution that combines efficient processing, reliable sealing, and broad compatibility for modern freeze-drying applications.

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