The only device that can accurately mimic the dynamic conditions of the digestive system
We are pleased to announce our new partnership with Triskelion, an innovative Dutch contract research organization that developed tiny-TIM to study the availability for absorption of oral (pharmaceutical) compounds. The tiny-TIM is an in vitro system that models the gastrointestinal tract in adults, children, and animals. It is now available for lease and purchase in the USA.
Compartments in the GI module simulate the shape and motility of the stomach and small intestine. A computerized peristaltic pump transports gastric content into the small intestinal compartment.
A syringe pump dispenses secretion fluids with high accuracy into the gastrointestinal compartments and fresh filtration and dialysis fluids through the membrane units.
In this module, sampling bottles collect filtrate or dialysis fluid from the small intestinal compartment. A controlled, FMI pump fills the bottles with a pre-determined weight of sample.
The tiny-TIM can be used to satisfy both pharmaceutical and nutritional applications, including bio-equivalence studies, drug-to-nutrient interactions, digestibility of complex meals.
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